EC Number |
Metals/Ions |
Reference |
---|
5.1.99.1 | Mn2+ |
increases activity to a smaller extent than Co2+ |
2437 |
5.1.99.1 | Mn2+ |
lower level of activation than Co2+ at higher concentrations |
2442 |
5.1.99.1 | Mn2+ |
presence of Mn2+ restores activity after incubation with EDTA |
693174 |
5.1.99.1 | more |
enzyme does not require tightly bound metal ions for activity, they are not released even after extensive dialysis at pH 2.4 |
2437 |
5.1.99.1 | more |
His12, Gln65, His91 and Glu141 provide a binding site for a divalent metal ion, as shown by binding of Co2+ |
653930 |
5.1.99.1 | more |
no activation of enzyme with Mg2+, Ni2+ |
693174 |
5.1.99.1 | Ni2+ |
activates |
726729 |
5.1.99.1 | Ni2+ |
increases activity to a smaller extent than Co2+ |
2437 |
5.1.99.1 | Ni2+ |
the enzyme is activated by divalent cations (Ni2+, Co2+, and Mg2+) |
726729 |
5.1.99.1 | Zn2+ |
increases activity to a smaller extent than Co2+ |
2437 |