EC Number |
Metals/Ions |
Reference |
---|
2.4.1.149 | Ca2+ |
about one third of the activity compared to Mn2+, recombinant enzyme |
658728 |
2.4.1.149 | Mg2+ |
about one third of the activity compared to Mn2+, recombinant enzyme |
658728 |
2.4.1.149 | more |
absolute requirement for divalent cations, not stimulated by Mg2+ |
638577 |
2.4.1.149 | Ca2+ |
activates, 48% as effective as Mn2+ |
638606 |
2.4.1.149 | Co2+ |
activates, 52% as effective as Mn2+ |
638606 |
2.4.1.149 | Cd2+ |
CdCl2 slightly stimulates |
489473 |
2.4.1.149 | more |
enzyme possesses 2 distinct metal binding sites, not activated by Ca2+, Mg2+, Zn2+, Fe2+, Cu2+, Ni2+, K+, Na+ |
638578 |
2.4.1.149 | Mn2+ |
essential for activity, neither Mg2+ nor Ca2+ can substitute for Mn2+ |
638575 |
2.4.1.149 | Mg2+ |
MgCl2 slightly stimulates |
489473 |
2.4.1.149 | Mn2+ |
MnCl2 stimulates 2.5fold, optimal concentration: 20 mM |
638577 |