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EC Number
Localization
Commentary
GeneOntology No.
Reference
3.6.1.71
mitochondrion
isoforms carrying a 42-nt N-terminal mitochondrial targeting sequence are localized to mitochondria
GO:0005739
AmiGO
QuickGO
755241
3.6.1.71
nucleolus
-
GO:0005730
AmiGO
QuickGO
740518
3.6.1.71
nucleolus
aprataxin localizes at sites of DNA damage induced by high low linear energy transfer radiation
GO:0005730
AmiGO
QuickGO
741072
3.6.1.71
nucleolus
GFP-aprataxin fusion protein colocalizes with nucleolin, nucleophosmin and UBF-1 in nucleoli. Inhibition of ribosomal DNA transcription alters the distribution of aprataxin in the nucleolus. Down-regulation of nucleolin by RNA interference does not affect aprataxin protein levels but abolishes its nucleolar localization
GO:0005730
AmiGO
QuickGO
740519
3.6.1.71
nucleoplasm
-
GO:0005654
AmiGO
QuickGO
740518
3.6.1.71
nucleus
-
GO:0005634
AmiGO
QuickGO
741055
,
750390
3.6.1.71
nucleus
the first nuclear localization signal located near the amino terminus of the long-form aprataxin is essential for its nuclear localization
GO:0005634
AmiGO
QuickGO
739862
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