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EC Number
Localization
Commentary
GeneOntology No.
Reference
3.4.21.106
cell membrane
-
-
653117
3.4.21.106
cell surface
-
GO:0009986
AmiGO
QuickGO
650510
,
687522
3.4.21.106
cytoplasm
hepsin is detected in the cytoplasm and membrane of hepatocytes. In ovarian tumor cells, cytoplasmic localization of hepsin is prevalent in mucinous, endometrioid and transitional cell carcinomas, while the majority of serous and clear cell carcinomas display membranous localization
GO:0005737
AmiGO
QuickGO
698324
3.4.21.106
cytoplasm
non-transmembrane isoform
GO:0005737
AmiGO
QuickGO
672315
3.4.21.106
membrane
-
GO:0016020
AmiGO
QuickGO
650281
,
651852
3.4.21.106
membrane
has an integral transmembrane domain near the N-terminus
GO:0016020
AmiGO
QuickGO
686903
3.4.21.106
membrane
hepsin is detected in the cytoplasm and membrane of hepatocytes. In ovarian tumor cells, cytoplasmic localization of hepsin is prevalent in mucinous, endometrioid and transitional cell carcinomas, while the majority of serous and clear cell carcinomas display membranous localization. Membrane-associated hepsin protein is present at desmosomal junctions, where it colocalizes with its putative proteolytic substrate hepatocyte growth factor
GO:0016020
AmiGO
QuickGO
698324
3.4.21.106
membrane
transmembrane isoform
GO:0016020
AmiGO
QuickGO
672315
3.4.21.106
microsome
-
-
650281
,
685451
,
707636
3.4.21.106
plasma membrane
-
GO:0005886
AmiGO
QuickGO
650510
,
651840
,
653117
,
653908
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