EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
   3.4.17.10 | extracellular |
secretion from neuroendocrine tissue |
- |
668816 |
| 3.4.17.10 | membrane |
- |
GO:0016020 AmiGO QuickGO |
668816, 669586, 683819, 683877, 698162, 81289, 81302, 81305 |
| 3.4.17.10 | membrane |
anchored to secretory granules via a C-terminal transmembrane insertion. The membrane-binding domain of the enzyme must adopt an alpha-helical configuration to bind to lipids and the enzyme may require another integral membrane chaperone protein to insert through the lipid bilayer in a transmembrane fashion |
GO:0016020 AmiGO QuickGO |
650156 |
| 3.4.17.10 | membrane |
bound |
GO:0016020 AmiGO QuickGO |
667483 |
| 3.4.17.10 | membrane |
membrane-associated via a C-terminal amphipathic sequence |
GO:0016020 AmiGO QuickGO |
683932 |
| 3.4.17.10 | membrane |
pH-dependent membrane anchor |
GO:0016020 AmiGO QuickGO |
81301 |
| 3.4.17.10 | membrane |
secretory granule membrane derived from trans-Golgi network, associated with detergent-resistant lipid domains, or rafts, within secretory granule membranes |
GO:0016020 AmiGO QuickGO |
652040 |
| 3.4.17.10 | membrane |
the enzyme is produced from pro-carboxypeptidase E and exists in soluble and membrane forms |
GO:0016020 AmiGO QuickGO |
753432 |
| 3.4.17.10 | membrane |
the enzyme is sorted into the secretory pathway via its C-terminal domain |
GO:0016020 AmiGO QuickGO |
668816 |
| 3.4.17.10 | more |
co-existence of chromogranin A and carboxypeptidase E in identical neuroendocrine cells in the thymus |
- |
708044 |
