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EC Number
Localization
Commentary
GeneOntology No.
Reference
3.1.6.1
cell surface
-
GO:0009986
AmiGO
QuickGO
709806
3.1.6.1
endoplasmic reticulum
-
GO:0005783
AmiGO
QuickGO
668717
3.1.6.1
endosome
-
GO:0005768
AmiGO
QuickGO
707966
3.1.6.1
extracellular
-
-
709806
3.1.6.1
intracellular
32% of arylsulfatase acivity is intracellular
GO:0005622
AmiGO
QuickGO
-
,
730337
3.1.6.1
lysosome
-
GO:0005764
AmiGO
QuickGO
135532
,
693036
,
707966
,
709618
,
709667
,
709806
,
730069
3.1.6.1
lysosome
63-kDa single-chain precursor protein localizes to pre-lysosomal compartments and tightly associates with organelle membranes. Proteolytically processed arylsulfatase G fragments of 34-, 18-, and 10-kDa are found in lysosomal fractions and lost their membrane association. Lysosomal transport of arylsulfatase G in the liver is independent of mannose 6-phosphate, sortilin, and Limp2. Mutation of glycosylation site N497 abrogates transport to lysosomes, due to impaired mannose 6-phosphate modification
GO:0005764
AmiGO
QuickGO
730056
3.1.6.1
lysosome
inside membrane-bound cytoplasmic vesicles
GO:0005764
AmiGO
QuickGO
681811
3.1.6.1
lysosome
inside membrane-bound cytoplasmic vesicles distributed throughout the cell body
GO:0005764
AmiGO
QuickGO
681811
3.1.6.1
lysosome
protein carries mannose 6-phosphate, indicating lysosomal sorting
GO:0005764
AmiGO
QuickGO
730022
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