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EC Number Localization Commentary GeneOntology No. Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64autophagic vacuole - - 750697
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64cytoplasm - GO:0005737 AmiGO QuickGO 732086
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64cytosol platelet GO:0005829 AmiGO QuickGO 646450
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64endosome - GO:0005768 AmiGO QuickGO 716970
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64endosome late endosome GO:0005768 AmiGO QuickGO 750697
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64endosome membranes of late endosome, MTMR2-MTMR13 complex GO:0005768 AmiGO QuickGO 665651
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64endosome MTM1 is present on ruffles at the plasma membrane, on early endosomes and partially on late endosomes GO:0005768 AmiGO QuickGO 715016
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64endosome MTM1 localizes to both early and late endosomes and associates with the hVPS15/hVPS34 complex. Both Rab7 and MTM1 bind to hVPS15, the hVPS34 adapter molecule that regulates hVPS34 activity through its interactions with Rab5 and Rab7. The WD40 domain of hVPS15 mediates binding to Rab5, Rab7 and MTM1. Consequently, binding of the hVPS15/hVPS34 complex to the Rab GTPases and MTM1 is mutually exclusive GO:0005768 AmiGO QuickGO 682936
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64endosome predominantly GO:0005768 AmiGO QuickGO 715992
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.64endosome treatment with multiple MAPK inhibitors results in a MTMR2 localization shift from Rab5-positive endosomes to the more proximal APPL1-positive endosomes GO:0005768 AmiGO QuickGO 732221
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