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EC Number
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2.7.7.92
nucleus
the crucial nuclear localization signal in the fish enzyme is bipartite and the functionality depends on a free N-terminus. Nuclear transport and enzymatic activity are independent functions. The sequence K5K6R7 is sufficient to direct GFP to the nucleus, and is necessary for the nuclear import of the CMP-Sia-synthetase in fish cells
GO:0005634
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692525
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