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Results 1 - 9 of 9
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EC Number Localization Commentary GeneOntology No. Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84cytosol - GO:0005829 AmiGO QuickGO 721135
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84cytosol OAS1 p42 isoform GO:0005829 AmiGO QuickGO 762506
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84mitochondrion OAS1 p46 isoform GO:0005739 AmiGO QuickGO 762506
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84more the CaaX motif (C = cysteine, a = aliphatic amino acid, X = terminal amino acid) in OAS1 is of key importance to the cellular localization, it is present in the C-terminal of only the p46 isoform, localization study, detailed overview. The wild-type OAS1 p42 isozyme is highly dispersed in the cytosol, but changes to a more organelle-associated protein when the CaaX motif is added. The same correlation between the CaaX motif and spatial distribution can be observed with endogenous OAS1 protein in IFN-beta treated HeLa cells (only p42) and HT-1080 cells (mainly p46) - 762506
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84more three distinct forms of 2'-5'OAS exist in human cells, that show distinct subcellular localizations - 721753
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84nucleus association of this form of OAS with membranes of the nuclear envelope and the rough endoplasmic reticulum GO:0005634 AmiGO QuickGO 721753
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84ribosome - GO:0005840 AmiGO QuickGO 721135
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84ribosome OAS3 is mainly associated with the ribosomal fraction GO:0005840 AmiGO QuickGO 721753
Display the word mapDisplay the reaction diagram Show all sequences 2.7.7.84rough endoplasmic reticulum association of this form of OAS with membranes of the nuclear envelope and the rough endoplasmic reticulum GO:0005791 AmiGO QuickGO 721753
Results 1 - 9 of 9
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