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EC Number
Localization
Commentary
GeneOntology No.
Reference
2.7.11.16
cell membrane
association of GRK6 with the cell membrane is mediated in part by the palmitoylation of cysteine residues that lie in a C-terminal region
-
674574
2.7.11.16
centrosome
GRK5 co-localizes with gamma-tubulin, centrin, and pericentrin in centrosomes. The centrosomal localization of GRK5 is observed predominantly at interphase and although its localization is not dependent on microtubules, it can mediate microtubule nucleation of centrosome
GO:0005813
AmiGO
QuickGO
725509
2.7.11.16
cytoplasm
-
GO:0005737
AmiGO
QuickGO
671352
,
726308
2.7.11.16
cytoplasm
the GRK5 subcellular distribution in the human striatal neurons is altered by its phosphorylation: phosphorylated GRK5 is found in plasma membrane and cytosolic fractions
GO:0005737
AmiGO
QuickGO
726308
2.7.11.16
cytosol
-
GO:0005829
AmiGO
QuickGO
661667
2.7.11.16
membrane
-
GO:0016020
AmiGO
QuickGO
661667
,
672408
,
685121
2.7.11.16
membrane
anchoring of GRK4 by palmitoyl residue at the C-terminus
GO:0016020
AmiGO
QuickGO
662921
2.7.11.16
membrane
anchoring via palmitoylation
GO:0016020
AmiGO
QuickGO
662767
2.7.11.16
membrane
cytosolic side of the plasma membrane
GO:0016020
AmiGO
QuickGO
762419
2.7.11.16
membrane
GRK5 protein does not undergo agonist-dependent translocation from cytosol to membranes as do beta-adrenergic receptor kinase and rhodopsin kinase, but rather appears to associate with membranes constitutively
GO:0016020
AmiGO
QuickGO
491154
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