EC Number   |
Localization |
GeneOntology No. |
Reference |
|---|
   2.7.11.15 | cell membrane |
- |
- |
725634 |
| 2.7.11.15 | centrosome |
- |
GO:0005813 AmiGO QuickGO |
739031 |
| 2.7.11.15 | cytoplasm |
- |
GO:0005737 AmiGO QuickGO |
725634 |
| 2.7.11.15 | cytoplasm |
GRK2 and GRK3 |
GO:0005737 AmiGO QuickGO |
661455 |
| 2.7.11.15 | cytoplasm |
predominantly cytoplasmic, enzyme activity depends upon its translocation from the cytoplasm to the membrane, the betagamma subunits of G proteins bind to enzyme and recruit it to the membrane, beta-ARK 1 binds to Gbeta2 |
GO:0005737 AmiGO QuickGO |
645013 |
| 2.7.11.15 | cytosol |
- |
GO:0005829 AmiGO QuickGO |
490989, 490992, 640698, 645001, 645003, 645009, 645011, 645021, 661667, 662153, 662767, 662911 |
| 2.7.11.15 | cytosol |
cardiac, total cytosolic activity amount to values almost 3times those of membrane activity, during myocardial ischemia the membrane activity of beta-ARK is increased, but the cytosolic activity is not altered |
GO:0005829 AmiGO QuickGO |
645024 |
| 2.7.11.15 | cytosol |
cytosolic enzyme, isoproterenol and platelet-activating factor induce translocation of beta-ARK from cytosol to membrane |
GO:0005829 AmiGO QuickGO |
490989 |
| 2.7.11.15 | cytosol |
GRK2 translocation from cytosol to the plasma membrane |
GO:0005829 AmiGO QuickGO |
674831 |
| 2.7.11.15 | cytosol |
in unstimulated cells enzyme is mainly located in the cytosol |
GO:0005829 AmiGO QuickGO |
645017 |
