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EC Number
Localization
Commentary
GeneOntology No.
Reference
2.7.1.154
actin filament
-
GO:0005884
AmiGO
QuickGO
761736
2.7.1.154
clathrin-coated vesicle
-
GO:0030136
AmiGO
QuickGO
761736
2.7.1.154
clathrin-coated vesicle
PI3K-C2alpha is closely associated with clathrin-coated pits and vesicles through its direct interaction via its N-terminal clathrin-binding domain
GO:0030136
AmiGO
QuickGO
761736
2.7.1.154
clathrin-coated vesicle
PI3KC2alpha
GO:0030136
AmiGO
QuickGO
645037
,
645044
2.7.1.154
Golgi trans-face
-
-
645044
2.7.1.154
juxtanuclear Golgi region
at high levels
-
640950
2.7.1.154
membrane
-
GO:0016020
AmiGO
QuickGO
739146
2.7.1.154
membrane
predominantly localised to intracellular membranes
GO:0016020
AmiGO
QuickGO
672858
2.7.1.154
more
both PI3K-C2alpha and PI3K-C2beta are co-localized with clathrin-coated pits and vesicles. PI3K-C2beta, but not PI3K-C2alpha, is highly co-localized with actin filament-associated clathrin-coated structures and required for actin filament formation at the clathrin-coated structures
-
761736
2.7.1.154
more
membrane translocation of PI3K-C2alpha in response to KCl
-
760780
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