EC Number |
Localization |
GeneOntology No. |
Reference |
---|
1.3.1.72 | cell surface |
hepatocellular carcinoma cells, hepatoblastoma cell line, and cervical adenocarcinoma-derived cell line |
GO:0009986 AmiGO QuickGO |
746181 |
1.3.1.72 | cytoplasm |
a predicted transmembrane (TM) domain-deleted DHCR24 mutation is localized to the cytoplasm |
GO:0005737 AmiGO QuickGO |
725752 |
1.3.1.72 | endoplasmic reticulum |
- |
GO:0005783 AmiGO QuickGO |
-, 686416, 725752, 745890, 746241, 746255, 746354, 764328 |
1.3.1.72 | endoplasmic reticulum membrane |
- |
GO:0005789 AmiGO QuickGO |
746354 |
1.3.1.72 | endoplasmic reticulum membrane |
DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains. The majority of the enzyme is associated with the endoplasmic reticulum membrane. The predicted membrane topology of DHCR24 consists of N-terminal transmembrane domains. The putative transmembrane domain is not essential for DHCR24 membrane association |
GO:0005789 AmiGO QuickGO |
744530 |
1.3.1.72 | endoplasmic reticulum membrane |
DHCR24 membrane association |
GO:0005789 AmiGO QuickGO |
746354 |
1.3.1.72 | endoplasmic reticulum membrane |
primarily, a putative transmembrane domain exists in the N-terminus of DHCR24 |
GO:0005789 AmiGO QuickGO |
746181 |
1.3.1.72 | Golgi apparatus |
- |
GO:0005794 AmiGO QuickGO |
746354 |
1.3.1.72 | membrane |
- |
GO:0016020 AmiGO QuickGO |
744737 |
1.3.1.72 | membrane |
bound |
GO:0016020 AmiGO QuickGO |
654502 |