EC Number |
Localization |
GeneOntology No. |
Reference |
---|
1.1.1.315 | endoplasmic reticulum |
pronounced 11-cis-retinol dehydrogenase activity is associated with both endoplasmic reticulum- and plasma membrane-enriched membrane fractions. In contrast, 11-cis-retinyl ester hydrolase activity is mostly recovered in plasma membrane-enriched fractions, while lecithin retinol acyl transferase LRAT activity is found only in endoplasmic reticulum-enriched membranes |
GO:0005783 AmiGO QuickGO |
170681 |
1.1.1.315 | endoplasmic reticulum |
the majority of 11-cis retinol dehydrogenase is associated with the smooth ER in retinal pigment epithelial cells. The enzyme is an integral membrane protein, anchored to membranes by two hydrophobic peptide segments. The catalytic domain of the enzyme is confined to a lumenal compartment and is not present on the cytosolic aspect of membranes |
GO:0005783 AmiGO QuickGO |
715709 |
1.1.1.315 | endoplasmic reticulum |
wild-type. All tested RDH5 mutants, including A294P, show an abnormal perinuclear localization in transfected cells and induce a redistribution of the ER marker calnexin |
GO:0005783 AmiGO QuickGO |
715455 |
1.1.1.315 | membrane |
- |
GO:0016020 AmiGO QuickGO |
690842 |
1.1.1.315 | membrane |
associated to membrane, and ssequence displays several potential membrane-spanning segments |
GO:0016020 AmiGO QuickGO |
715421 |
1.1.1.315 | membrane |
pronounced 11-cis-retinol dehydrogenase activity is associated with both endoplasmic reticulum- and plasma membrane-enriched membrane fractions. In contrast, 11-cis-retinyl ester hydrolase activity is mostly recovered in plasma membrane-enriched fractions, while lecithin retinol acyl transferase LRAT activity is found only in endoplasmic reticulum-enriched membranes |
GO:0016020 AmiGO QuickGO |
170681 |
1.1.1.315 | microsome |
- |
- |
692700, 715451 |
1.1.1.315 | plasma membrane |
pronounced 11-cis-retinol dehydrogenase activity is associated with both endoplasmic reticulum- and plasma membrane-enriched membrane fractions. In contrast, 11-cis-retinyl ester hydrolase activity is mostly recovered in plasma membrane-enriched fractions, while lecithin retinol acyl transferase LRAT activity is found only in endoplasmic reticulum-enriched membranes |
GO:0005886 AmiGO QuickGO |
170681 |