EC Number   |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
|---|
    2.4.1.17 | -999 |
- |
more |
- |
488716, 488746, 488747, 488755, 488790, 488794, 692035 |
| 2.4.1.17 | -999 |
- |
more |
bisubstrate kinetics of wild-type and mutant isozyme UGT1A6 |
694254 |
| 2.4.1.17 | -999 |
- |
more |
co-expression of both UGT1A1 and UGT1A4 increases the Vmax values of UGT1A6-catalyzed serotonin and diclofenac O-glucuronide formation |
692032 |
| 2.4.1.17 | -999 |
- |
more |
coexpression of UGT1A1 decreases the Vmax value of UGT1A4-catalyzed imipramine N-glucuronide formation but has no effect on UGT1A4-catalyzed trifluoperazine N-glucuronide formation. Coexpression of UGT1A6 has no effect on UGT1A4-catalyzed imipramine N-glucuronide formation but increases the Km and Vmax of UGT1A4-catalyzed trifluoperazine N-glucuronide formation |
692032 |
| 2.4.1.17 | -999 |
- |
more |
different kinetic profiles of isozymes with different hormone substrates, overview |
659571 |
| 2.4.1.17 | -999 |
- |
more |
effect of temperature |
488714 |
| 2.4.1.17 | -999 |
- |
more |
effect of UDP-N-acetylglucosamine as activator |
488746 |
| 2.4.1.17 | -999 |
- |
more |
enzyme kinetics with substrate gemfibrozil follow Michaelis-Menten kinetics |
692034 |
| 2.4.1.17 | -999 |
- |
more |
frusemide glucuronidation followed MichaelisMenten kinetics in all tissues, kinetics of different microsome types from liver and kidney, overview |
690855 |
| 2.4.1.17 | -999 |
- |
more |
glucuronidation of the non-selective substrate 4-methylumbelliferone by mutant chimeric UGT2B7-15(61194)-7 and isozyme UGT2B15 followed MichaelisMenten and weak substrate inhibition kinetics, respectively, overview |
690847 |
