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EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Reference
2.3.1.12
-999
-
more
-
642164
2.3.1.12
-999
-
more
binding constants of multienzyme complex components and regulatory enzymes, overview
663011
2.3.1.12
-999
-
more
complex component interactions among each other and with regulatory enzyme pyruvate dehydrogenase kinase isozyme 2, overview, dissociation constants of interaction of L2 and recombinant GST-L2 with PDK isozyme 2, reduced PDK2 binding to E2-E1, reversible bifunctional binding to L2 with the mandatory singly held transition fits the proposed 'hand-over-hand' movement of a kinase dimer to access E1 without dissociating from the complex
662151
2.3.1.12
-999
-
more
the complex assembly and maintainance is regulated by thermodynamic homeostasis or entropy-enthalpy compensation
661632
2.3.1.12
0.013
-
acetyl-CoA
catalytic domain after expression in Escherichia coli
486225
2.3.1.12
0.022
-
acetyl-CoA
wild-type enzyme
486228
2.3.1.12
0.028
-
acetyl-CoA
S558A mutant
486228
2.3.1.12
0.03
0.1
acetyl-CoA
-
486203
2.3.1.12
0.036
-
acetyl-CoA
H610C mutant
486228
2.3.1.12
0.052
-
acetyl-CoA
N614D mutant
486228
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