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EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Reference
1.1.1.149
-999
-
more
kinetics
668428
1.1.1.149
-999
-
more
rapid activity decrease upon homogenization
285997
1.1.1.149
0.0002
-
NADPH
20-oxo and 20alpha-hydroxy-steroids, pH 7.0
285998
1.1.1.149
0.0002
-
NADPH
wild type, pH 7.5, 37°C
656526
1.1.1.149
0.0004
-
5alpha-pregnane-3alpha,20alpha-diol
mutant L308V, pH 7.4, 25°C
711423
1.1.1.149
0.0005
-
5alpha-pregnan-3,20-dione
at pH 7.4 and 37°C
740126
1.1.1.149
0.0006
-
isatin
at pH 7.4 and 37°C
740126
1.1.1.149
0.0006
-
progesterone
at pH 7.4 and 37°C
740126
1.1.1.149
0.0006
-
progesterone
NADPH, intact cells
285997
1.1.1.149
0.0007
-
5alpha-pregnan-20alpha-ol-3-one
pH 7.0, 25°C
655220
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