EC Number |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
---|
3.5.4.5 | 0.31 |
- |
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine |
leukemia enzyme |
209657 |
3.5.4.5 | 2.8 |
- |
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine |
- |
209657 |
3.5.4.5 | 3.9 |
- |
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodocytosine |
- |
209657 |
3.5.4.5 | 0.33 |
- |
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)cytosine |
- |
209657 |
3.5.4.5 | 0.66 |
- |
1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)cytosine |
- |
209657 |
3.5.4.5 | 0.27 |
- |
1-beta-D-arabinofuranosylcytosine |
- |
209657 |
3.5.4.5 | 0.51 |
- |
1-beta-D-arabinofuranosylcytosine |
- |
209657 |
3.5.4.5 | 0.0092 |
- |
2',2'-difluorodeoxycytidine |
i.e. gemcitabine, variation of plasma gemcitabine between 0.9 and 9.2 microM |
695606 |
3.5.4.5 | 0.0957 |
- |
2',2'-difluorodeoxycytidine |
- |
209663 |
3.5.4.5 | 0.0726 |
- |
2',2'-difluorodeoxyuridine |
i.e. dFdU, variation of plasma ranges between 24.9 and 72.6 microM |
695606 |