EC Number |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
---|
3.1.1.84 | 0.00027 |
- |
cocaine |
pH 7.4, mutant enzyme Q55E |
650108 |
3.1.1.84 | 0.00064 |
- |
cocaine |
pH 7.4, wild-type enzyme |
650108 |
3.1.1.84 | 0.00075 |
- |
cocaine |
pH 7.4, mutant enzyme Q55A |
650108 |
3.1.1.84 | 0.0011 |
- |
(-)-cocaine |
mutant enzyme A199S/F227A/S287G/A328W/E441D, pH not specified in the publication, at 25°C |
716278 |
3.1.1.84 | 0.0012 |
- |
cocaine |
pH 7.4, mutant enzyme L407A |
650108 |
3.1.1.84 | 0.0015 |
- |
cocaine |
mutant enzyme T172R/G173Q/L196C/I301C, at 37°C, pH not specified in the publication |
728856 |
3.1.1.84 | 0.0016 |
- |
cocaethylene |
pH 7.4, wild-type enzyme |
650108 |
3.1.1.84 | 0.0021 |
- |
cocaine |
mutant enzyme T172R/G173Q/G4C/S10C, at 37°C, pH not specified in the publication |
728856 |
3.1.1.84 | 0.0029 |
- |
cocaine |
mutant enzyme T172R/G173Q, at 37°C, pH not specified in the publication |
728856 |
3.1.1.84 | 0.0031 |
- |
(-)-cocaine |
mutant enzyme A199S/S287G/A328W/Y332G, at 25°C, in 0.1 M potassium phosphate, pH 7.5 |
714702 |