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EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Commentary	Reference
2.1.1.157	0.5	-	dimethylglycine	pH 8.8, 37°C, recombinant wild-type enzyme	659286
2.1.1.157	4.9	-	dimethylglycine	recombinant enzyme, pH 7.4, 37°C, with S-adenosyl-L-methionine	657578
2.1.1.157	7.5	-	dimethylglycine	pH 8.8, 37°C, recombinant mutant P171Q	659286
2.1.1.157	2.8	-	N,N-dimethylglycine	-	689964
2.1.1.157	3.76	-	N,N-dimethylglycine	pH 7.2, 37°C	695924
2.1.1.157	3.76	-	N,N-dimethylglycine	pH 7.3, 37°C, recombinant enzyme	720836
2.1.1.157	0.144	-	S-adenosyl-L-methionine	cosubstrate: sarcosine	689964
2.1.1.157	0.15	-	S-adenosyl-L-methionine	cosubstrate: N,N-dimethylglycine	689964
2.1.1.157	0.16	-	S-adenosyl-L-methionine	recombinant enzyme, pH 7.4, 37°C, with glycine	657578
2.1.1.157	0.18	-	S-adenosyl-L-methionine	pH 8.8, 37°C, recombinant wild-type enzyme, with dimethylglycine	659286

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Release 2023.1 (January 2023)