EC Number   |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Reference |
|---|
   3.4.21.27 | 0.603 |
- |
L-pyroGlu-L-Pro-L-Arg-4-nitroanilide |
mutant enzyme K192Q, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 0.655 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-K170A mutant |
691011 |
| 3.4.21.27 | 0.757 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-wild type |
691011 |
| 3.4.21.27 | 0.764 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-K179A mutant |
691011 |
| 3.4.21.27 | 0.81 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-R173A mutant |
691011 |
| 3.4.21.27 | 0.812 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-R171A mutant |
691011 |
| 3.4.21.27 | 0.828 |
- |
L-pyroGlu-L-Pro-L-Arg-4-nitroanilide |
mutant enzyme I151A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 0.829 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-catalytic domain-K175A mutant |
691011 |
| 3.4.21.27 | 0.852 |
- |
L-pyroGlu-L-Pro-L-Arg-4-nitroanilide |
mutant enzyme K192A, in 50 mM Tris-HCl, 150 mM NaCl, 5 mM CaCl2, 0.5% (w/v) bovine serum albumin, pH 7.3, at 37°C |
717844 |
| 3.4.21.27 | 0.943 |
- |
L-pyroglutamyl-L-prolyl-L-argininyl-p-nitroanilide |
fXIa-wild type |
691011 |
