EC Number |
Inhibitors |
Structure |
---|
7.6.2.1 | 1-monoolein |
0.5 mM significantly reduce the P-glycoprotein protein expression, 0.1 mM of 1-monoolein does not have any significant effect on the expression of P-glycoprotein |
|
7.6.2.1 | 1-monostearin |
0.5 mM significantly reduce the P-glycoprotein protein expression, 0.1 mM of 1-monostearin does not have any significant effect on the expression of P-glycoprotein |
|
7.6.2.1 | 4-(2-aminoethyl)benzenesulfonyl fluoride |
flippase activity for 1-oleoyl-2-[6-(7-nitrol-2-1,3-benzonadiol-4-yl)amino]-sn-glycerophosphoethanolamine is inhibited by 72% at 5 mM 4-(2-aminoethyl)benzenesulfonyl fluoride, flippase activity for 1-oleoyl-2-[6-(7-nitrol-2-1,3-benzonadiol-4-yl)amino]-sn-glycerophosphocholine is inhibited by 75% at 5 mM 4-(2-aminoethyl)benzenesulfonyl fluoride |
|
7.6.2.1 | 4-hydroxy-2-nonenal |
- |
|
7.6.2.1 | 5,5'-dithiobis(2-nitrobenzoic acid) |
flippase activity for 1-oleoyl-2-[6-(7-nitrol-2-1,3-benzonadiol-4-yl)amino]-sn-glycerophosphoethanolamine is inhibited by 80% at 20 mM 5,5'-dithiobis(2-nitrobenzoic acid), flippase activity for 1-oleoyl-2-[6-(7-nitrol-2-1,3-benzonadiol-4-yl)amino]-sn-glycerophosphocholine is inhibited by 60% at 20 mM 5,5'-dithiobis(2-nitrobenzoic acid) |
|
7.6.2.1 | acrolein |
- |
|
7.6.2.1 | AlFx |
trapping of MsbA with 0.8 mM AlFx results in incomplete inhibition of activity |
|
7.6.2.1 | AMP-PNP |
- |
|
7.6.2.1 | azide |
- |
|
7.6.2.1 | Bcl-2 |
PLS3 and tBid may form a bidirectional positive feedback loop that is antagonized by Bcl-2 |
|