EC Number   |
Inhibitors |
Structure |
|---|
   5.6.1.6 | 2-(pyridin-4-yl)-4H-benzo[h]chromen-4-one |
i.e. UCCF-029. Concentrations below 50 nM increase the open probability of the channel, favouring the channel transition to the an activated state. Levels above 50 nM determine inhibition of the channel by a reduction of the open time. UCCF-029 does not interfere with binding of ATP |
   |
| 5.6.1.6 | 2-sulfonatoethyl methanethiosulfonate |
enzyme residues A299, R303, N306, S307, F310, and F311 are accessible to intracellular 2-sulfonatoethyl methanethiosulfonate in both the open and closed states |
|
| 5.6.1.6 | 3-[(3-trifluoromethyl)phenyl]-5-[(4-carboxyphenyl)methylene]-2-thioxo-4-thiazolidinone |
CFTR(inh)-172, potent CFTR inhibitor, exerts nonspecific effects regarding reactive oxygen species production, mitochondrial failure, and activation of the NF-kappa B signaling pathway, independently of CFTR inhibition |
|
| 5.6.1.6 | 5-nitro-2(3-phenylpropylamino)benzoate |
- |
|
| 5.6.1.6 | 5-nitro-2-(3-phenylpropylamine)benzoic acid |
- |
|
| 5.6.1.6 | 5-[(4-carboxyphenyl)methylene]-2-thioxo-3-[(3-trifluoromethyl)phenyl]4-thiazolidinone |
- |
|
| 5.6.1.6 | 8-(4-chlorophenylthio)-AMP |
the ATPase activity of the enzyme is reduced in the presence of higher concentrations of 8-(4-chlorophenylthio)-AMP |
|
| 5.6.1.6 | 8-azido-ATP |
is retained at nucleotide-binding domain 1, NBD1 at low temperature even in the absence of bivalent cations |
|
| 5.6.1.6 | adenylyl-imidodiphosphate |
modulation of the on-rate of venom binding for intraburst block |
|
| 5.6.1.6 | adenylyliminodiphosphate |
- |
|
