EC Number   |
Inhibitors |
Structure |
|---|
    5.1.1.7 | (2-(4-amino-4-carboxybutyl) aziridine-2-carboxylic acid) |
AziDAP |
   |
| 5.1.1.7 | 1,2-benzisothiazolidine 3-one |
30 nM, complete inhibition |
|
| 5.1.1.7 | 2-(4-amino-4-carboxybutyl)-aziridine-2-carboxylate |
substrate mimic, irreversible inhibition |
|
| 5.1.1.7 | 2-(4-amino-4-carboxybutyl)aziridine-2-carboxylic acid |
irreversible |
|
| 5.1.1.7 | 2-nitro-5-thiocyanatobenzoate |
30 nM, complete inhibition |
|
| 5.1.1.7 | 3-Chlorodiaminopimelate |
the inhibitor is converted to a tight-binding transition state analog at the active site of this enzyme |
|
| 5.1.1.7 | 3-fluoro analogs of diaminopimelate |
potent competitive inhibitors |
|
| 5.1.1.7 | 4-Oxo-1,2,3,4-tetrahydro-pyridine-2,6-dicarboxylic acid |
very poor inhibitor |
|
| 5.1.1.7 | 5,5'-dithiobis(2-nitrobenzoic acid) |
30 nM, complete inhibition |
|
| 5.1.1.7 | acetone |
inactivation by 50% acetone |
|
