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Results 1 - 2 of 2
EC Number Inhibitors Commentary Structure
Display the word mapDisplay the reaction diagram Show all sequences 4.2.99.B1EDTA 5 or 10 mM, inhibits beta-pol dRP lyase activity, in contrast to the 8-kDa domain dRP lyase activity that is slightly stimulated. Higher concentrations, 20 and 40 mM restore the beta-pol activity to a level similar to that in the absence of EDTA. The inhibitory effect of EDTA on the beta-pol ectivity is reversed by 25-100 mM NaCl. The same concentration has no effect on the activity of the 8-kDa domain Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 4.2.99.B1pyridoxal 5'-phosphate 2 mM, results in 95 and 75% inhibition of the dRP lyase activity of beta-pol and the 8-kDa domain, respectively. The mutant K72A of the 8-kDa domain and the full-length protein beta-pol exhibit 90 and 80% loss of activity, respectively Go to the Ligand Summary Page
Results 1 - 2 of 2