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EC Number
Inhibitors
Commentary
Structure
4.2.3.24
ADP
about 20% inhibition at 15 mM
4.2.3.24
ATP
more than 5fold reduction in enzyme activity at 15 mM ATP
4.2.3.24
Co2+
inhibitory above 0.5 mM
4.2.3.24
CTP
potent inhibitor, 75fold inhibition at 10 mM
4.2.3.24
Cu2+
complete inhibition
4.2.3.24
diphosphate
potent inhibitor
4.2.3.24
Mn2+
inhibitory above 0.5 mM
4.2.3.24
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not inhibited by phosphomevalonic acid
4.2.3.24
Ni2+
-
4.2.3.24
Zn2+
complete inhibition
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