EC Number   |
Inhibitors |
Structure |
|---|
   4.1.1.B12 | alpha-difluoromethylarginine |
alpha-difluoromethylarginine also inhibits the enzyme and enhances the inhibitory effect of alpha-difluoromethylornithine from 14% to 20% inhibition at 5 mM |
   |
| 4.1.1.B12 | alpha-difluoromethylornithine |
inhibitor of ornithine decarboxylase, inhibitory |
|
| 4.1.1.B12 | alpha-difluoromethylornithine |
ornithine decarboxylase suicide inhibitor, dose-dependent inhibition of both lysine and ornthine decarboxylase activities |
|
| 4.1.1.B12 | alpha-difluoromethylornithine |
alpha-DFMO, a suicide inhibitor, at 5 mM for 72 h, it inhibits membrane-associated ODC activity. Following exposure to alpha-DFMO, the putrescine content in the cells declineds, while the norspermidine content increases over 2fold. Partial inhibition of putrescine synthesis by alpha-DFMO results in increased norspermidine production in the cells suggesting that the suicide inhibitor may also act as an abiotic stress agent |
|
| 4.1.1.B12 | L-ornithine |
competitive |
|
