EC Number   |
Inhibitors |
Structure |
|---|
    4.1.1.90 | 2,3,5,6-Tetrachloro-4-pyridinol |
TCP, anticoagulant action, effective in vitro inhibitor of the carboxylase |
   |
| 4.1.1.90 | 2-chloro-3-phytyl-1,4-naphthoquinone |
chloro-K, effective in vivo antagonist of vitamin K, inhibits the enzyme in an competitive fashion |
|
| 4.1.1.90 | 2-chloro-3-phytyl-1,4-naphthoquinone |
- |
|
| 4.1.1.90 | 5-mercapto-1-methylthiotetrazole |
- |
|
| 4.1.1.90 | anti-carboxylase antiserum |
effect of anti-carboxylase antiserum on carboxylase activity: under the conditions employed the carboxylation is inhibited by 80%, with parallel inhibition of CO2 incorporation into FLEEL and proPT28 (synthetic peptide) |
|
| 4.1.1.90 | Boc-(2S,4S)-4-methylglutamic acid-Glu-Val |
competitive inhibitor, FLEEL as substrate |
|
| 4.1.1.90 | Boc-Ser(OPO4)-Ser(OPO4)-Leu-OMe |
inhibits the enzyme apparently competitively with regard to other peptide substrate |
|
| 4.1.1.90 | bromoacetyl-FLEEL peptide |
the His6-carboxylase is irreversibly inactivated. Up to 85% of the carboxylase activity is lost over a period of 120 min |
|
| 4.1.1.90 | CN- |
enzyme is blocked by mM concentrations of CN- |
|
| 4.1.1.90 | CsCl |
- |
|
