EC Number   |
Inhibitors |
Structure |
|---|
    3.5.1.3 | 2,2,2-Trifluoroethanol |
more than 2 M: irreversible inactivation |
   |
| 3.5.1.3 | 2-Chloroethanol |
more than 2 M: irreversible inactivation |
|
| 3.5.1.3 | 5,5'-dithiobis-(2-nitrobenzoic acid) |
Ellman's reagent |
|
| 3.5.1.3 | 5,5'-dithiobis-(2-nitrobenzoic acid) |
0.02 mM: complete inhibition; Ellman's reagent |
|
| 3.5.1.3 | 6-diazo-5-oxo-L-norleucine |
DON, completely |
|
| 3.5.1.3 | alpha-ketosuccinamate |
10 mM: 75% inhibition |
|
| 3.5.1.3 | dioxane |
up to 5% dioxane: no effect on hydrolysis of ethyl alpha-keto-glutarate or glutaramate, at 10% dioxane: slight, 5-10% inhibition |
|
| 3.5.1.3 | ethanol |
more than 2 M: irreversible inactivation |
|
| 3.5.1.3 | ethanol |
0.05 M: no inhibition |
|
| 3.5.1.3 | Glutaramate |
competitive inhibition, 10 mM glutaramate, hydrolysis of methyl alpha-ketoglutarate: 43% inhibition, hydrolysis of ethyl alpha-ketoglutarate: 34% inhibition |
|
