EC Number   |
Inhibitors |
Structure |
|---|
   3.4.23.34 | (D)-His-Pro-Phe-His-Leu-PSI(CH2-NH)-Leu-Val-Tyr |
i.e. H-77, with reduced isostere as replacement of the-CO-NH- of the peptide bond |
   |
| 3.4.23.34 | 1,2-epoxy-3-(p-nitrophenoxy)propane |
ir |
|
| 3.4.23.34 | alpha2-Macroglobulin |
at pH 5.5, RNAse as substrate, at a molar ratio of enzyme/inhibitor of 0.5:1 to 2:1, above a ratio of 2:1 the excess enzyme is not inhibited, structural changes in alpha2-macroglobulin upon complex formation, no inhibition with oxidized insulin B-chain as substrate |
|
| 3.4.23.34 | Ascaris pepsin inhibitor |
- |
|
| 3.4.23.34 | CCACCAACACAACTAAACTCCAC |
inhibitory part, additionally the molecule has the conserved sequence GATCTCACTCCTTCGCAGTATTCGCGAGCC at its 5'-side, 4.5% inhibition (2 nM inhibitor /2 nM cathepsin E) |
|
| 3.4.23.34 | CCACCACCACAACAAAACTCCAC |
inhibitory part, additionally the molecule has the conserved sequence GATCTCACTCCTTCGCAGTATTCGCGAGCC at its 5'-side, 31.0% inhibition (2 nM inhibitor /2 nM cathepsin E) |
|
| 3.4.23.34 | CCACCACCACAACGAAACTCCAC |
inhibitory part, additionally the molecule has the conserved sequence GATCTCACTCCTTCGCAGTATTCGCGAGCC at its 5'-side, 14.0% inhibition (2 nM inhibitor /2 nM cathepsin E) |
|
| 3.4.23.34 | CCACCACCACAATAAAACTCCAC |
inhibitory part, additionally the molecule has the conserved sequence GATCTCACTCCTTCGCAGTATTCGCGAGCC at its 5'-side, 33.5% inhibition (2 nM inhibitor /2 nM cathepsin E) |
|
| 3.4.23.34 | CCATCACTACAACAAAACTCCAC |
inhibitory part, additionally the molecule has the conserved sequence GATCTCACTCCTTCGCAGTATTCGCGAGCC at its 5'-side, 11.0% inhibition (2 nM inhibitor /2 nM cathepsin E) |
|
| 3.4.23.34 | CCCATAGGGATCACTCCCTCCAC |
inhibitory part, additionally the molecule has the conserved sequence GATCTCACTCCTTCGCAGTATTCGCGAGCC at its 5'-side, 22.3% inhibition (2 nM inhibitor /2 nM cathepsin E) |
|
