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EC Number
Inhibitors
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Structure
3.4.22.B24
calpain inhibitor IV
0.1 mg/ml, irreversible, attacks the active site of m-calpain nucleophilically, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired
3.4.22.B24
calpeptin
0.075 mg/ml, reversible, reacts with the active site of both my-calpain and m-calpain, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired
3.4.22.B24
PD 151746
0.1 mg/ml, reversible, binds predominantly to the Ca2+-binding site of my-calpain, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired
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