EC Number   |
Inhibitors |
Structure |
|---|
   3.2.2.27 | 1'-cyano-2'-deoxyuridine |
- |
   |
| 3.2.2.27 | 4(6)-aminouracil |
- |
|
| 3.2.2.27 | 4-hydroxymercuribenzoate |
1 mM, 94% inhibition |
|
| 3.2.2.27 | 4-methylindole |
4-methylindole is an adenine isostere incapable of hydrogen bonding, and its pair with Thy is inherently prone to spontaneous opening, structure of hUNGin a complex with DNA containing a Thy:4-methylindole pair, a DNA mimic, overview |
|
| 3.2.2.27 | 5-Azauracil |
strong inhibition |
|
| 3.2.2.27 | 5-halogenated uracil analogues |
- |
|
| 3.2.2.27 | Alba protein |
a small basic chromatin protein, repression of UDG1 activity |
|
| 3.2.2.27 | apurinic/apyrimidinic site |
the enzyme is product-inhibited by both uracil and apurinic/apyrimidinic sites |
|
| 3.2.2.27 | Bacillus subtilis Ung inhibitor |
- |
|
| 3.2.2.27 | Cd2+ |
complete inhibition at 5 mM |
|
