EC Number |
Inhibitors |
Structure |
---|
3.2.2.14 | 5-phosphoribose 1-diphosphate |
PRPP, inorganic polyphosphates, affinity of 5-phosphoribose 1-pyrophosphate for the enzyme is dependent on the activator concentration , inhibition mechanism with 5-phosphoribose 1-pyrophosphate is competitive with GTP |
|
3.2.2.14 | 7-methylguanosine-5'-triphosphate |
- |
|
3.2.2.14 | adenosine |
addition of 1.4 mM, inhibition 54.7% |
|
3.2.2.14 | ADP-ribose |
addition of 1-1.4 mM, inhibition 74.4% |
|
3.2.2.14 | AMP |
addition of 1.4 mM AMP, inhibition 92.5% |
|
3.2.2.14 | ATP |
- |
|
3.2.2.14 | Cd2+ |
1 mM |
|
3.2.2.14 | CTP |
- |
|
3.2.2.14 | Cu2+ |
1 mM |
|
3.2.2.14 | D-ribose-5-phosphate |
addition of 1.4 mM, inhibition 42.3% |
|