EC Number   |
Inhibitors |
Structure |
|---|
    3.2.1.24 | (1R,6R,7R,8S)-7,8-dihydroxy-5-thia-1-thioniabicyclo[4.3.0]nonane chloride |
synthetic inhibitor, selective and potent inhibition at 1 mM, 97% inhibition of the activity of the liver lysosomal fraction at pH 4.0, 100% at pH 6.5 |
   |
| 3.2.1.24 | (1S,2R,3R,8R,8aR)-3-[(arylmethoxy)methyl]octahydroindolizine-1,2,8-triol |
- |
|
| 3.2.1.24 | (1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol |
- |
|
| 3.2.1.24 | (2R,3R,4S)-2-(aminomethyl)pyrrolidine-3,4-diol |
1 mM, 81% inhibition, competitive |
|
| 3.2.1.24 | (2R,3R,4S)-2-(aminomethyl)pyrrolidine-3,4-diol |
1 mM, 51% inhibition |
|
| 3.2.1.24 | (2R,3R,4S)-2-([(1R)-2,3-dihydro-1H-inden-1-ylamino]methyl)pyrrolidine-3,4-diol |
IC50 is 0.017 mM |
|
| 3.2.1.24 | (2R,3R,4S)-2-([[(1R)-1-hydroxyethyl]amino]methyl)pyrrolidine-3,4-diol |
1 mM, 75% inhibition, competitive |
|
| 3.2.1.24 | (2R,3R,4S)-2-([[(1R)-1-hydroxyethyl]amino]methyl)pyrrolidine-3,4-diol |
1 mM, 39% inhibition |
|
| 3.2.1.24 | (2R,3R,4S)-2-([[(1R)-2-hydroxy-1-phenylethyl]amino]methyl)pyrrolidine-3,4-diol |
- |
|
| 3.2.1.24 | (2R,3R,4S)-2-([[(1S)-1-hydroxyethyl]amino]methyl)pyrrolidine-3,4-diol |
1 mM, 66% inhibition, competitive |
|
