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EC Number Inhibitors Commentary Structure
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.169(3aS,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol NAG-thiazoline, inhibits also other functionally related enzymes Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.169(3aS,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-propyl-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol NButGT, selective O-GlcNAcase inhibitor Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.169(6S,7R,8R)-8-acetamido-6,7-dihydroxy-5-(hydroxymethyl)-N-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxamide PUGNAc-imidazole hybrid Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1691,2-dideoxy-2'-butyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline - Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1691,2-dideoxy-2'-ethyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline - Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1691,2-dideoxy-2'-isobutyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline - Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1691,2-dideoxy-2'-isopropyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline - Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1691,2-dideoxy-2'-methyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline an inhibitor that mimics the oxazoline intermediate proposed in the catalytic mechanism of family 20 glycoside hydrolases, is shown to act as a potent competitive inhibitor. NAG-thiazoline is therefore a potent inhibitor of O-GlcNAcase, binding about 21000fold more tightly than the parent saccharide, N-acetyl-beta-D-glucosaminide Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1691,2-dideoxy-2'-methyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline NAG-thiazoline Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.1691,2-dideoxy-2'-pentyl-alpha-D-glucopyranoso-[2,1-d]-DELTA2'-thiazoline - Go to the Ligand Summary Page
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