EC Number   |
Inhibitors |
Structure |
|---|
   3.2.1.146 | 1,2:3,4-di-O-isopropylidene-6-S-(D-galactofuranosyl)-6-thio-alpha-D-galactopyranose |
pH 4.9, 37°C, 80% enzyme activity at 0.3 mM, beyond that about 75% enzyme activity, 0.2-1.0 mM inhibitor |
   |
| 3.2.1.146 | 2-propyl 3-deoxy-4-S-(beta-D-galactofuranosyl)-4-thio-alpha-D-xylo-hexopyranoside |
pH 4.9, 37°C, weak inhibitory activity, about 85% enzyme activity at 1 mM, 0.2-1.0 mM inhibitor |
|
| 3.2.1.146 | 4-aminophenyl beta-D-1-thio-galactofuranose |
- |
|
| 3.2.1.146 | 4-methylphenyl 1-thio-beta-D-galactofuranoside |
low inhibitory activity with 30% inhibition at 0.25 mM |
|
| 3.2.1.146 | 4-nitrophenyl beta-D-1-thio-galactofuranose |
- |
|
| 3.2.1.146 | D-galactono-1,4-lactone |
- |
|
| 3.2.1.146 | D-galactono-1,4-lactone |
competitive inhibition, 50% inhibition in the presence of 1 mM ZnCl2, CaCl2, NiCl2 or AgNO3 |
|
| 3.2.1.146 | D-galactono-1,4-lactone |
pH 4.9, 37°C, strong inhibitor, about 40% enzyme activity at 0.1 mM, 10% enzyme activity at 0.2 mM, less than 10% beyond 0.2 mM |
|
| 3.2.1.146 | D-galactono-1,4-lactone |
resembles the transition state of the hydrolysis |
|
| 3.2.1.146 | methyl 5-S-(beta-D-galactofuranosyl)-6-deoxy-5-thio-alpha-L-altrofuranoside |
competitive inhibitor |
|
