EC Number |
Inhibitors |
Structure |
---|
2.7.1.24 | acetyl-CoA |
inhibition at higher concentrations; inhibition at higher concentrations |
|
2.7.1.24 | CoA |
inhibition at higher concentrations; inhibition at higher concentrations |
|
2.7.1.24 | coenzyme A |
- |
|
2.7.1.24 | CTP |
enzymatic activity is regulated by CTP which strongly binds the enzyme at a site overlapping that of the leading substrate, dephosphocoenzyme A, thereby obscuring the binding site and limiting catalysis. 16% residual activity at 1 mM CTP |
|
2.7.1.24 | deoxycholate |
inactivation, 0.2% |
|
2.7.1.24 | EDC4 |
EDC4 is also known as Ge-1, Hedls, RCD-8. EDC4 strongly inhibits the dephospho-CoA kinase activity of coenzyme A synthase in vitro |
|
2.7.1.24 | malonyl-CoA |
inhibition at higher concentrations; inhibition at higher concentrations |
|
2.7.1.24 | more |
no inhibition by F- with or without phosphate, adenosine, 2-, 3- or 5-adenylic acids, ADP, NAD+, NADH, deamino-NAD+, adenosine diphosphate ribose |
|
2.7.1.24 | more |
excess concentrations of CoA inhibit growth |
|
2.7.1.24 | UTP |
at high concentrations |
|