EC Number |
Inhibitors |
Structure |
---|
2.7.1.159 | 1D-myo-inositol-1,3,4,5-tetrakisphosphate |
competitive |
|
2.7.1.159 | 1D-myo-inositol-1,3,4,6-tetrakisphosphate |
competitive |
|
2.7.1.159 | 1D-myo-inositol-3,4,5,6-tetrakisphosphate |
inhibits the 5/6-kinase activities, but not the phosphorylation of ATF-2 |
|
2.7.1.159 | curcumin |
inhibits both the free enzyme and the COP9 signalosome complex-associated kinase |
|
2.7.1.159 | Mn2+ |
activates the protein phopshorylation, but inhibits the inositol-1,3,4-trisphosphate 5/6-kinase reaction |
|
2.7.1.159 | more |
enzyme activity is unaffected by protein kinase C, protein kinase A, and Ca2+/calmodulin |
|
2.7.1.159 | protein kinase A |
slight inhibition of enzyme activity with ATF-2 as substrate |
|