EC Number |
Inhibitors |
Structure |
---|
2.7.1.145 | (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil |
IC50: 0.0277 mM for reaction with thymidine and 0.0158 mM for reaction with 2'-deoxycytidine |
|
2.7.1.145 | (E)-5-(2-bromovinyl)-2'-deoxyuridine |
IC50: 0.00257 mM for reaction with thymidine and 0.00194 mM for reaction with 2'-deoxycytidine |
|
2.7.1.145 | (E)-5-(2-bromovinyl)-2'-deoxyuridine |
- |
|
2.7.1.145 | (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-monophosphate |
IC50: 0.0026 mM, reaction with thymidine, fusion protein with glutathione S-transferase |
|
2.7.1.145 | (E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate |
IC50: 0.0069 mM, reaction with thymidine, fusion protein with glutathione S-transferase. The inhibitor is efficiently metabolized to its 5'-mono-, 5'-di- and 5'-triphosphate derivatives in the insect cell culture and abundently incorporated into the insect cell DNA |
|
2.7.1.145 | 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil |
IC50: 0.0163 mM for reaction with thymidine and 0.0154 mM for reaction with 2'-deoxycytidine |
|
2.7.1.145 | 1-beta-D-arabinofuranosylcytosine |
IC50: 0.0534 mM for reaction with thymidine and 0.089 mM for reaction with 2'-deoxycytidine |
|
2.7.1.145 | 1-beta-D-arabinofuranosylthymidine |
IC50: 0.0648 mM for reaction with thymidine and 0.0348 mM for reaction with 2'-deoxycytidine |
|
2.7.1.145 | 1-beta-D-arabinofuranosyluracil |
IC50: 0.057 mM for reaction with thymidine and 0.058 mM for reaction with 2'-deoxycytidine |
|
2.7.1.145 | 2',2'-difluorodeoxycytidine |
IC50: 0.145 mM for reaction with thymidine and 0.102 mM for reaction with 2'-deoxycytidine |
|