Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Inhibitors

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Image of 2D Structure
Search for synonyms (with exact matching search term)

Search term:

Results 1 - 10 of 101 > >>
download as CSV
download all results as CSV
EC Number Inhibitors Commentary Structure
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.127(2'S)-1D-1,2-O-[(2'-phosphoryloxy)propane-1',3'-diyl]-myo-inositol 4,5-bisphosphate synthetic bicyclic inositol trisphosphate S epimer, IC50 is 0.156 mM Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1271D-myo-inositol 1,3,4,5-tetrakisphosphate marked product inhibition, isoforms A and B Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1271D-myo-inositol 1,3,4,5-tetrakisphosphate product inhibition, IC50 is 0.013 mM Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1271D-myo-inositol 1,4,5-trisphosphate recombinant, catalytically active fragment of isoform C, substrate inhibition by high concentrations Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1271D-myo-inositol 1,4,5-trisphosphate substrate inhibition of the catalytic domain Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1272,3-diphosphoglycerate - Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1272-[3,5-dimethyl-1-(4-nitrophenyl)-1H-pyrazol-4-yl]-5,8-dinitro-1H-benzo[de]isoquinoline-1,3(2H)-dione BIP-4, BIP-4 is competitive to Ins(1,4,5)P3 and shows high selectivity for the Ins(1,4,5)P3 binding pocket, BIP-4 does not block the actin bundling activity of ITPKA Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1273',4',7,8-tetrahydroxyflavone mixed-type versus ATP, noncompetitive versus 1D-myo-inositol 1,4,5-trisphosphate Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1273',4',7,8-tetrahydroxyflavone inhibition of isozyme A, mixed-type versus ATP, noncompetitive versus 1D-myo-inositol 1,4,5-trisphosphate Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1273',4',7,8-tetrahydroxyflavone the point mutant K336Q reveals a drastically reduced inhibition by THF. Substitution of Lys336 leads to a 260fold increase in the IC50. On the other hand, kinetic parameters of the enzyme with respect to both substrates are nearly unchanged. This region shows high homology between IP3K isoforms. Go to the Ligand Summary Page
Results 1 - 10 of 101 > >>
download as CSV
download all results as CSV