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EC Number
Inhibitors
Commentary
Structure
2.3.1.168
arsenite
strong inhibition
2.3.1.168
CoA
product inhibition, competitive to acyl-CoA, noncompetitive to dihydrolipoamide
2.3.1.168
Mg2+
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2.3.1.168
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limited proteolysis by trypsin results in the complete loss of the overall activity of the enzyme complex, but does not affect dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; NEM and thiamine diphosphate have no effect
2.3.1.168
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2.3.1.168
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inhibition tests of the multienzyme complex with sera from patients suffering the possibly autoimmune diseases idopathic dilated cardiomyopathy and dilated cardiomyopathy to perform epitope mapping, overview
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