EC Number |
Inhibitors |
Structure |
---|
1.5.1.15 | (2S)-2-[[4-[(6aR)-3-amino-1,9-dioxo-5,6,6a,7-tetrahydro-4H-imidazo[1,5-f]pteridin-8-yl]benzoyl]amino]pentanedioic acid |
i.e. LY345899 |
|
1.5.1.15 | 5,10-methylenetetrahydrofolate |
substrate inhibition of wild-type enzyme and mutant Q183E, no inhibition of mutant Q183A |
|
1.5.1.15 | EDTA |
NAD+ dependent enzyme from Ehrlich ascites tumor cells |
|
1.5.1.15 | menadione |
substrate inhibition of wild-type enzyme and mutant Q183A, no inhibition of mutant Q183E |
|
1.5.1.15 | NADH |
substrate inhibition |
|
1.5.1.15 | S-adenosyl-L-methionine |
allosteric inhibitor, enzyme contains a binding site at the C-terminus |
|
1.5.1.15 | Zn2+ |
- |
|