EC Number   |
Inhibitors |
Structure |
|---|
    1.4.1.16 | (2E,6S)-6-aminohept-2-enedioic acid |
- |
   |
| 1.4.1.16 | (2E,6S)-6-aminohept-2-enedioic acid |
compound identified by molecular dynamics simulation, the predicted binding free energy of the compound with the enzyme is -29.86 kcal/mol, compared to -34.70 kcal/mol for diaminopimelate |
|
| 1.4.1.16 | (2S)-2-amino-6-methylideneheptanedioic acid |
- |
|
| 1.4.1.16 | (2S)-2-amino-6-methylideneheptanedioic acid |
compound identified by molecular dynamics simulation, the predicted binding free energy of the compound with the enzyme is -31.38 kcal/mol, compared to -34.70 kcal/mol for diaminopimelate |
|
| 1.4.1.16 | (2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid |
competitive inhibition |
|
| 1.4.1.16 | (2S,5S)-2-amino-3(3-carboxy-2-isoxazolin-5-yl)propanoic acid |
- |
|
| 1.4.1.16 | (3S)-3-amino-4-{[(1S)-1-carboxy-2-phenylethyl]amino}-4-oxobutanoic acid |
2% inhibition at 3 mM |
|
| 1.4.1.16 | (5R)-5-[(2S)-2-amino-2-carboxyethyl]-4,5-dihydro-1,2-oxazole-3-carboxylic acid |
compound identified by molecular dynamics simulation, the predicted binding free energy of the compound with the enzyme is -19.77 kcal/mol, compared to -34.70 kcal/mol for diaminopimelate |
|
| 1.4.1.16 | (5S)-5-[(2S)-2-amino-2-carboxyethyl]-4,5-dihydro-1,2-oxazole-3-carboxylic acid |
- |
|
| 1.4.1.16 | (5S)-5-[(2S)-2-amino-2-carboxyethyl]-4,5-dihydro-1,2-oxazole-3-carboxylic acid |
compound is selectively potent to Porphyromonas gingivalis strains W83 and ATCC 33277 with minimum inhibitory concentration values of 773 microM and 1.875 mM, respectively |
|
