EC Number   |
Inhibitors |
Structure |
|---|
    1.3.2.3 | 5,5'-dithiobis(2-nitrobenzoic acid) |
thiol-modifying agent |
   |
| 1.3.2.3 | Acriflavine |
reaction with phenazine methosulfate |
|
| 1.3.2.3 | Acriflavine |
diminished by addition of FAD or FMN |
|
| 1.3.2.3 | Atebrin |
reaction with ferricytochrome inhibited, reaction with phenazine methosulfate not |
|
| 1.3.2.3 | Cu2+ |
strong inhibition |
|
| 1.3.2.3 | glutathione |
the enzyme activity is inhibited by 60% by reduced glutathione (GSH) |
|
| 1.3.2.3 | H2O2 |
GALDH is inactivated by hydrogen peroxide due to selective oxidation of cysteine 340, located in the cap domain |
|
| 1.3.2.3 | iodoacetic acid |
- |
|
| 1.3.2.3 | L-galactono-1,4-lactone |
inhibitory at concentrations above 10 mM |
|
| 1.3.2.3 | L-galactono-1,4-lactone |
inhibitory at concentrations above 2 mM |
|
