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EC Number Inhibitors Commentary Structure
Display the word mapDisplay the reaction diagram Show all sequences 1.21.3.6H2O2 inhibits oxidation of 2',3,4,4',6'-pentahydroxychalcone Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 1.21.3.6Phenylthiourea competitive inhibition Go to the Ligand Summary Page
Display the word mapDisplay the reaction diagram Show all sequences 1.21.3.6Phenylthiourea modeling of enzyme-phenylthiourea complex. The inhibitor binds with the hydrophobic pocket of the dinuclear copper center. The phenyl ring of Phe262 and the imidazole ring of His245 form hydrophobic interactions with the aromatic ring of the inhibitor. The sulfur atom of the inhibitor replaces the hydroxo-bridge, which is essential for catalysis Go to the Ligand Summary Page
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