EC Number   |
Inhibitors |
Structure |
|---|
    1.19.6.1 | diazene |
inhibits proton reduction |
   |
| 1.19.6.1 | H2 |
inhibits both N2 and diazene reduction |
|
| 1.19.6.1 | NIFI1,2 |
a regulatory protein, inhibits nitrogenase by competing with Fe protein for binding to the MoFe protein, NifI1,2 inhibits ATP- and MoFe protein-dependent oxidation of the Fe protein, and NIFI1,2 binding prevents association of the two nitrogenase components, the inhibition is relieved by 2-oxoglutarate. NIFI1,2 is unable to bind to an AlF4- stabilized Fe protein:MoFe protein complex. Both nifI1 and nifI2 are required for regulation in vivo |
|
| 1.19.6.1 | nitrate |
2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide suppresses the inhibition by nitrate |
|
| 1.19.6.1 | O2 |
complete reversible inhibition, reversibility decreases by increasing the time of exposure to O2 |
|
| 1.19.6.1 | sodium nitroprusside |
inhibits acetylene-reduction activity of nitrogenase by 1 mM |
|
