EC Number   |
Inhibitors |
Structure |
|---|
   1.17.4.5 | brodifacoum |
- |
   |
| 1.17.4.5 | bromadiolone |
- |
|
| 1.17.4.5 | chlorophacinone |
- |
|
| 1.17.4.5 | Difenacoum |
- |
|
| 1.17.4.5 | difethialone |
- |
|
| 1.17.4.5 | glycerol |
concentrations up to 30% v/v inhibit enzyme activity up to 88% |
|
| 1.17.4.5 | more |
not inhibited by warfarin |
|
| 1.17.4.5 | more |
VKORC1 mutant Y137F is resistant against inhibition by warfarin, but not against inhibition by other antocoagulants, overview |
|
| 1.17.4.5 | more |
non-VKOR, warfarin-sensitive enzyme, while hVKORL is mainly insensitive to inhibition by warfarin, but about 30% of hVKORL1 is inhibited by 0.005 mM warfarin, VKORL1 is warfarin sensitive, but not affect warfarin dosage requirements |
|
| 1.17.4.5 | more |
evaluation of warfarin resistance using TALENs-mediated vitamin K epoxide reductase knockout HEK293 cells, overview |
|
