EC Number |
Inhibitors |
Structure |
---|
1.14.15.18 | 1,25-Dihydroxycholecalciferol |
calcitriol |
|
1.14.15.18 | 1,25-Dihydroxycholecalciferol |
calcitriol; in vivo only inhibitory in vitamin D receptor containing cells, therefore: negative feedback inhibition is mediated by the enzyme through liganded vitamin D receptor |
|
1.14.15.18 | 1,25-Dihydroxycholecalciferol |
calcitriol; decreases mRNA expression in less differentiated cells like Caco-2/AQ and COGA-1A and -1E |
|
1.14.15.18 | 22-oxacalcitriol |
vitamin D3 analogue, inhibits in vitro and in vivo |
|
1.14.15.18 | 25-hydroxy-3-deoxy-2-oxavitamin D3 |
vitamin D3 analogue, competitive inhibition |
|
1.14.15.18 | 25-hydroxydihydrotachysterol3 |
- |
|
1.14.15.18 | 25-hydroxyvitamin D2 |
CYP27B1 shows inhibition when substrate concentrations in the membrane are greater than 4 times Km, more pronounced with 25-hydroxyvitamin D3 than with 25-hydroxyvitamin D2 |
|
1.14.15.18 | 25-hydroxyvitamin D3 |
CYP27B1 shows inhibition when substrate concentrations in the membrane are greater than 4 times Km, more pronounced with 25-hydroxyvitamin D3 than with 25-hydroxyvitamin D2 |
|
1.14.15.18 | 3-deoxy-2-oxa-9(11)-didehydro-25-hydroxyvitamin D3 |
vitamin D3 analogue, competitive inhibition |
|
1.14.15.18 | A-homo-3-deoxy-2-oxa-25-hydroxyvitamin D3 |
vitamin D3 analogue, competitive inhibition |
|