EC Number |
Inhibitors |
Structure |
---|
1.13.12.6 | alpha,alpha'-dipyridyl |
slight inhibition |
|
1.13.12.6 | chlorpromazine |
which binds to human plasma alpha 1-acid glycoprotein, shows an inhibitory effect on the luminescence of Cypridina luciferin, both in the presence of human plasma alpha 1-acid glycoprotein and a recombinant Cypridina luciferase |
|
1.13.12.6 | Cypndina gamma-globulin |
Cypridina luciferase is completely inhibited by a rabbit antibody to Cypridina luciferase |
|
1.13.12.6 | dithiothreitol |
- |
|
1.13.12.6 | more |
not inhibited by N-ethylmaleimide, N-methylmaleimide, iodoacetamide and p-chloromercuribenzoate |
|
1.13.12.6 | more |
Apogon luciferase is not inhibited by a rabbit antibody to Cypridina luciferase |
|
1.13.12.6 | Sodium azide |
slight inhibition |
|
1.13.12.6 | sodiumdodecylsulfate |
approx. 1 mM, complete inactivation |
|
1.13.12.6 | Urea |
at 5.0 M urea, the half-time of the enzyme is 45 min, at 6.0 M urea 8 min, and at 7.5 M urea, the enzyme is inactivated within 1 min. r´Reversible, non-competitive inhibition of the luciferase activity occurs at concentrations up to 1.5 M |
|