EC Number   |
Inhibitors |
Structure |
|---|
    1.1.1.77 | ascorbate |
0.025 mM FeCl3 and 0.035 mM ascorbate causes a 90% enzyme inactivation after 120 min = inactivation of metal-catalyzed oxidation; several amino-acids prevent the inactivation; under aerobic conditions 0.025 mM FeCl3 causes a 50% enzyme inactivation after 120 min |
   |
| 1.1.1.77 | Fe2+ |
under anaerobic conditions 0.01 mM Fe2+ and 0.1 mM H2O2 had the effect of 85% enzyme inactivation after 2 min, with addition of 0.0001 mM catalase the inactivation is only 25% after 2 min and with addition of 0.01 mM superoxide dismutase instead of catalse the inactivation is again 82% after 2 min |
|
| 1.1.1.77 | Fe3+ |
0.025 mM FeCl3 and 0.035 mM ascorbate causes a 90% enzyme inactivation after 120 min = inactivation of metal-catalyzed oxidation; several amino-acids prevent the inactivation; under aerobic conditions 0.025 mM FeCl3 causes a 50% enzyme inactivation after 120 min |
|
| 1.1.1.77 | H2O2 |
under anaerobic conditions 0.01 mM Fe2+ and 0.1 mM H2O2 had the effect of 85% enzyme inactivation after 2 min, with addition of 0.0001 mM catalase the inactivation is only 25% after 2 min and with addition of 0.01 mM superoxide dismutase instead of catalse the inactivation is again 82% after 2 min |
|
| 1.1.1.77 | iodoacetate |
- |
|
| 1.1.1.77 | L-1,2-propanediol |
above 25 mM: substrate inhibition |
|
| 1.1.1.77 | N-ethylmaleimide |
- |
|
| 1.1.1.77 | p-chloromercuribenzoate |
- |
|
